Table 3.

miRNAs showing significantly different levels in NASH grouped by fibrosis stage.

F2			F3			F4
miRNA	logFC	Adj. p val.	miRNA	logFC	Adj. p val.	miRNA	logFC	Adj. p val.
miR-193a-5p	0.41	4.77E-02	miR-193a-5p	0.72	2.00E-04	miR-193a-5p	0.88	2.32E-03
miR-19b-3p	-0.79	4.77E-02	miR-378d	0.48	4.97E-03	miR-4484	0.63	1.44E-02
miR-3135a	-0.46	4.77E-02	miR-378e	0.43	1.32E-02	miR-378g	0.51	1.79E-02
miR-378d	0.35	4.77E-02	miR-4484	0.45	1.32E-02	miR-6873-3p	-1.24	3.08E-02
miR-378e	0.35	4.77E-02	miR-378a-3p	0.38	1.50E-02
miR-4534	-0.46	4.77E-02	miR-6780a-5p	0.82	2.59E-02
miR-649	-0.59	4.77E-02
miR-670-3p	0.37	4.77E-02
miR-6769a-5p	0.22	4.77E-02
miR-6852-5p	0.27	4.77E-02
miR-25-3p	-0.61	4.83E-02
miR-330-3p	0.25	4.83E-02
miR-548ay-5p	-0.51	4.83E-02
miR-548d-5p	-0.63	4.83E-02

miRNA levels were assessed by sequencing and are shown relative to NAFL. Adjusted p value threshold ≤0.05. F0/F1 showed no significant differences to NAFL.

Adj. p val., adjusted p value; logFC, log₂ fold change; miRNA, microRNA; NAFL, non-alcoholic fatty liver; NASH, non-alcoholic steatohepatitis.