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. 2021 Dec 30;18(1):48–58. doi: 10.3988/jcn.2022.18.1.48

Table 2. Independent predictors of mortality and disability in patients with Guillain-Barré syndrome.

Characteristics Mortality (n=11,146) Disability* (n=10,144)
Hazard ratio 95% CI p Hazard ratio 95% CI p
Age (yr)
Each 10-year increase 2.02 1.95–2.10 <0.001 1.10 1.04–1.12 <0.001
Sex
Female 0.55 0.49–0.61 <0.001 0.88 0.78–1.00 0.053
Male 1.00 Reference 1.00 Reference
Income level
Low 1.36 1.21–1.53 <0.001 1.05 0.90–1.22 0.535
Middle 1.11 0.98–1.26 0.103 1.00 0.86–1.16 0.968
High 1.00 Reference 1.00 Reference
Hospital type
Referral hospital 0.83 0.75–0.91 <0.001 0.94 0.83–1.06 0.305
Nonreferral hospital 1.00 Reference 1.00 Reference
Hospitalization period
≥30 days 0.99 0.88–1.12 0.906 3.36 2.92–3.87 <0.001
<30 days 1.00 Reference 1.00 Reference
IVIG
Yes 1.21 1.08–1.34 0.001 1.46 1.28–1.68 <0.001
No 1.00 Reference 1.00 Reference
Plasmapheresis
Yes 1.02 0.69–1.50 0.933 1.92 1.46–2.54 <0.001
No 1.00 Reference 1.00 Reference
Tracheostomy
Yes 1.92 1.61–2.30 <0.001 2.85 2.41–3.38 <0.001
No 1.00 Reference 1.00 Reference

*GBS patients who had no physical disability at the time of GBS diagnosis; Income levels were classified into three categories: 1) low (poorest 30% of the population), 2) middle (31%–70% of the population), and 3) high (richest 30% of the population).

CI, confidence interval; GBS, Guillain-Barré syndrome; IVIG, intravenous immunoglobulin.