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. 2021 Nov 29;41(2):e108591. doi: 10.15252/embj.2021108591

Figure EV1. Over‐representation of Aβ APRs in tau tangles and amyloid plaques.

Figure EV1

  1. Subcellular localization of proteins found in amyloid plaques (Xiong et al, 2019a, b).
  2. No over‐representation was observed of any Aβ regions in Tau tangles isolated from human AD brains (Drummond et al, 2020a, b). Hippocampal formation data set from Human Protein Atlas was used as background. Statistics: Hypergeometric test with Bonferroni correction. *P ≤ 0.05.
  3. Over‐representation of C‐terminal APR in Aβ amyloid plaques isolated from human AD brains. (Drummond et al, 2017a, b). Hippocampal formation data set from Human Protein Atlas was used as background. Statistics: Hypergeometric test with Bonferroni correction. *P ≤ 0.05, **P ≤ 0.01, ****P ≤ 0.0001.