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. Author manuscript; available in PMC: 2022 Jan 17.
Published in final edited form as: J Am Chem Soc. 2021 Jul 2;143(27):10462–10476. doi: 10.1021/jacs.1c05470

Figure 13.

Figure 13.

(a) Brain uptake results (% injected dose per gram, ID/g) from the in vivo biodistribution study of 64Cu-LS-4 in 11-month old 5xFAD mice (green) vs age-matched WT mice (cyan), at 2 min, 1 h, and 4 h postinjection. Error bars represent standard deviations (n = 3), and the statistical analysis was evaluated according to one-way ANOVA (**p < 0.01, ****p < 0.001). (b) Autoradiography images of brain sections from 5xFAD and WT mice at different time points during the biodistribution studies.