Table 3.

Structural Findings and Structural/Functional Phenotypes in the Three Perimetric Groups

Characteristics	Central Scotoma (n = 54)	Other Scotomata (n = 14)	No Scotoma (n = 8)	P Value
SD-OCT phenotype
Severe	52 (96.3%)	9 (64.3%)	4 (50%)	<0.001
Symmetric (across the fovea)	51 (94.4%)	12 (85.7%)	8 (100%)	0.302
External limiting membrane involvement	38 (70.4%)	6 (42.9%)	1 (12.5%)	<0.001
FAF findings
Hyperautofluorescence within normal foveal hypoautofluorescence	15 (28.8%)	7 (58.3%)	0 (0%)	0.038
mfERG findings, group 1: 2: 3*	3:40:6 (6.1:81.6:12.2%)	4:6:2 (33.3:50:16.7%)	3:5:0 (37.5:62.5:0%)	0.017

SD-OCT, spectral-domain optical coherence tomography; FAF, fundus autofluorescence; mfERG, multifocal electroretinography.

^*Group 1, paracentral dysfunction with relatively preserved central/peripheral function; group 2, homogeneous central/paracentral dysfunction; group 3, widespread dysfunction over the whole area tested.