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. 2022 Jan 17;2022(1):CD015029. doi: 10.1002/14651858.CD015029
Outcome Number of studies Overview of effect by study Comparison used in each study Effect direction per study (positive ▲; negative ▼; no change/mixed effects/conflicting findings ◀▶)
Outcome category: transmission outcomes
Number of cases detected 1 observational screening study (Hoehl 2020) Hoehl 2020: the study aims to evaluate the practical application of self‐performed high‐frequency antigen tests in a school setting. 10,768 of these tests (99.4%) were recorded to have been valid and 113 negative, 47 (0.43%) were recorded as invalid and 21 (0.19%) as positive (either true or false). The study found that 0.15% of all antigen tests (16 tests) gave false‐positive results. False‐positive results were seen predominantly when the local incidence in the general population was low. In four cases, the study participant reported that a PCR had detected a SARS‐CoV‐2 infection, but the antigen test was negative, indicating a false negative. No asymptomatic infection was detected in this study.  Least intense measure Negative ▼