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. 2021 Dec 29;5(1):3–7. doi: 10.1021/acsptsci.1c00236

Figure 1.

Figure 1

Experimental approach used to identify statistically overrepresented fragments in a list of active DHCR7 inhibiting medications. molBLOCKS was used to fragment known 7-DHC-elevating medications within the FDA-approved medications and isolate chemical structures present in each compound.