Table 1. Screened Peptides and the Predicted MIC and AFIa.
| Predicted
MIC/μM (probability/%) |
||||||
|---|---|---|---|---|---|---|
| No. | Sequences | C. albicans | C. krusei | C. neoformans | C. parapsilosis | AFI/μM (probability/%) |
| 1 | KWCFRVCYRGICYRKCR | 1.41(99.1) | 4.25(95.0) | 0.20(63.4) | 16.79(94.4) | 2.11(56.3) |
| 2 | RRWCFRVCYRGFCYRKCR | 1.07(99.2) | 5.22(96.6) | 0.22(72.7) | 20.9(98.7) | 2.25(68.8) |
| 3 | KWCFRVCYRGICYRRCR | 1.87(99.1) | 5.22(95.4) | 0.17(56.0) | 18.25(95.3) | 2.34(50.5) |
| 4 | MRLRKCHKPLTLRLVPWKKQIM | 0.86(99.3) | 9.48(93.1) | 3.70(98.5) | 12.91(96.0) | 4.44(80.5) |
| 5 | MTKILLIVKRLRTVYTKRCLCFRA | 4.15(99.4) | 7.90(78.7) | 1.66(97.7) | 10.87(99.6) | 4.93(74.0) |
| 6 | MYSVFISSIFLFLKIRFKLYPR | 1.18(99.5) | 7.94(91.9) | 5.03(99.3) | 18.98(98.5) | 5.47(81.2) |
| 7 | MRPKWKKKRMRRLKRKRKQRRARYK | 3.59(99.0) | 5.29(70.8) | 4.47(91.7) | 14.5(83.7) | 5.92(49.7) |
| 8 | MNKIFRVIFSKILGRLIVT | 6.94(99.9) | 9.23(97.8) | 1.18(99.1) | 17.65(98.5) | 6.04(88.0) |
| 9 | MTKKQKRKKGIKTKSAGRFGARYGRRIRKAI | 8.71(94.3) | 6.74(67.2) | 4.03(80.0) | 12.52(65.3) | 7.38(29.9) |
| 10 | MKYKKLWALAGIALSCNLLLTA | 1.94(99.5) | 19.59(90.1) | 5.18(99.1) | 16.91(91.8) | 7.60(78.1) |
| 11 | VFQFLGRIIHHVGNFVHGFSHVF | 10.24(99.9) | 8.77(91.1) | 6.63(99.8) | 7.75(98.9) | 8.24(88.9) |
| 12 | MLKKKFGFVFLVCFVIFHSCK | 13.32(99.9) | 8.43(90.8) | 6.74(96.7) | 8.01(98.8) | 8.83(80.1) |
| 13 | YHKIHKVWHIIMKLLAHI | 37.07(99.8) | 9.06(98.3) | 6.51(99.8) | 5.40(96.3) | 10.43(94.3) |
| 14 | YFISCAIHFKILKIRSAAKRREHTKLR | 5.42(97.4) | 10.5(76.9) | 5.33(89.7) | 40.38(63.6) | 10.52(41.4) |
| 15 | MATKKKVVKKAVKKVAKKAPKKAVKKVAKKK | 47.94(92.6) | 8.06(78.3) | 0.84(64.7) | 38.56(68.1) | 10.59(31.9) |
| 16 | PVLKELKSVQKTKSGDTLY | 58.66(99.5) | 29.96(95.0) | 5.79(99.9) | 26.13(97.3) | 22.71(87.2) |
a
The bold represents the screened top three peptides.