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. 2021 Dec 8;13(1):99–104. doi: 10.1021/acsmedchemlett.1c00556

Table 2. Experimental MIC and AFI of the Screened Peptidesa.

    Experimental MIC/μM
 
No. Sequences C. albicans SC 5314 C. krusei IFM 56881 C. neoformans H99 C. parapsilosis ATCC22019 AFI/μM
1 KWCFRVCYRGICYRKCR 14.28 28.56 1.79 7.14 8.5
2 RRWCFRVCYRGFCYRKCR 4.07 4.07 1.02 1.02 2.0
3 KWCFRVCYRGICYRRCR 14.1 28.2 3.53 7.05 10.0
4 MRLRKCHKPLTLRLVPWKKQIM >92.2 >92.2 92.2 >92.2 >92.2
5 MTKILLIVKRLRTVYTKRCLCFRA 43.75 21.88 5.47 43.75 21.9
6 MYSVFISSIFLFLKIRFKLYPR >92.44 >92.44 >92.44 >92.44 >92.4
7 MRPKWKKKRMRRLKRKRKQRRARYK >73.77 >73.77 2.31 18.44 >21.9
8 MNKIFRVIFSKILGRLIVT 14.23 56.92 7.12 14.23 16.9
9 MTKKQKRKKGIKTKSAGRFGARYGRRIRKAI >70.71 >70.71 8.84 4.42 21.0
10 MKYKKLWALAGIALSCNLLLTA >105.7 >105.7 >105.7 >105.7 >105.7
11 VFQFLGRIIHHVGNFVHGFSHVF >94.99 >94.99 >94.99 >94.99 >95.0
12 MLKKKFGFVFLVCFVIFHSCK >101.5 >101.5 >101.5 >101.5 >101.5
13 YHKIHKVWHIIMKLLAHI 28.06 7.02 7.02 14.03 11.8
14 YFISCAIHFKILKIRSAAKRREHTKLR 77.88 19.47 38.94 77.88 46.3
15 MATKKKVVKKAVKKVAKKAPKKAVKKVAKKK >74.87 >74.87 37.44 >74.87 >63.0
16 PVLKELKSVQKTKSGDTLY >119.94 >119.94 >119.94 >119.94 >119.9
a

The bold highlights the MIC values less than 10 μM.