Table 2. Experimental MIC and AFI of the Screened Peptidesa.
Experimental
MIC/μM |
||||||
---|---|---|---|---|---|---|
No. | Sequences | C. albicans SC 5314 | C. krusei IFM 56881 | C. neoformans H99 | C. parapsilosis ATCC22019 | AFI/μM |
1 | KWCFRVCYRGICYRKCR | 14.28 | 28.56 | 1.79 | 7.14 | 8.5 |
2 | RRWCFRVCYRGFCYRKCR | 4.07 | 4.07 | 1.02 | 1.02 | 2.0 |
3 | KWCFRVCYRGICYRRCR | 14.1 | 28.2 | 3.53 | 7.05 | 10.0 |
4 | MRLRKCHKPLTLRLVPWKKQIM | >92.2 | >92.2 | 92.2 | >92.2 | >92.2 |
5 | MTKILLIVKRLRTVYTKRCLCFRA | 43.75 | 21.88 | 5.47 | 43.75 | 21.9 |
6 | MYSVFISSIFLFLKIRFKLYPR | >92.44 | >92.44 | >92.44 | >92.44 | >92.4 |
7 | MRPKWKKKRMRRLKRKRKQRRARYK | >73.77 | >73.77 | 2.31 | 18.44 | >21.9 |
8 | MNKIFRVIFSKILGRLIVT | 14.23 | 56.92 | 7.12 | 14.23 | 16.9 |
9 | MTKKQKRKKGIKTKSAGRFGARYGRRIRKAI | >70.71 | >70.71 | 8.84 | 4.42 | 21.0 |
10 | MKYKKLWALAGIALSCNLLLTA | >105.7 | >105.7 | >105.7 | >105.7 | >105.7 |
11 | VFQFLGRIIHHVGNFVHGFSHVF | >94.99 | >94.99 | >94.99 | >94.99 | >95.0 |
12 | MLKKKFGFVFLVCFVIFHSCK | >101.5 | >101.5 | >101.5 | >101.5 | >101.5 |
13 | YHKIHKVWHIIMKLLAHI | 28.06 | 7.02 | 7.02 | 14.03 | 11.8 |
14 | YFISCAIHFKILKIRSAAKRREHTKLR | 77.88 | 19.47 | 38.94 | 77.88 | 46.3 |
15 | MATKKKVVKKAVKKVAKKAPKKAVKKVAKKK | >74.87 | >74.87 | 37.44 | >74.87 | >63.0 |
16 | PVLKELKSVQKTKSGDTLY | >119.94 | >119.94 | >119.94 | >119.94 | >119.9 |
The bold highlights the MIC values less than 10 μM.