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Human entheseal stromal cells produce chemokines and adhesion molecules important for leukocyte recruitment. Stromal cells were isolated from human entheseal sites and stimulated with the fungal adjuvant mannan (1 mg/ml) for 24 h. A–D Supernatant was analyzed for IL-8, IL-6, CCL2 and CCL20 protein (n = 3). E, F Expression of the adhesion molecules ICAM-1 and VCAM-1 was analyzed by FACS, and median fluorescence intensity was quantified (n = 3). Paired t test (*p < 0.05, **p < 0.01)
