Table 1.
Clinical characteristics of 182 ICC patients (unmatched) based on cNFIB expression levels
| Variables | Low cNFIB (n = 91) |
High cNFIB (n = 91) |
P value |
|---|---|---|---|
| Age, year, > 60/≤60 | 46/45 | 37/54 | 0.1804 |
|
Gender, male/female Ascites, present/absent |
54/37 8/83 |
46/45 11/80 |
0.2333 0.4671 |
| Hepatolithiasis, present/absent | 3/88 | 2/89 | 0.6502 |
| HbsAg, positive/negative | 28/63 | 23/68 | 0.4092 |
| CA19–9, > 22/≤22 | 65/26 | 56/35 | 0.1576 |
| Tumor size (cm), > 5/≤5 | 54/37 | 47/44 | 0.2965 |
| Tumor number, multiple/solitary | 38/53 | 20/71 | 0.0042 |
| Differentiation, poor/well-moderate | 73/18 | 58/33 | 0.0133 |
| MVI, present/absent | 12/79 | 8/83 | 0.3431 |
| Lymph node, positive/negative | 22/69 | 11/80 | 0.0343 |
| Cirrhosis, with/without | 7/84 | 11/80 | 0.3206 |
| TNM stage, III/I- II | 70/21 | 49/42 | 0.0011 |
ICC intrahepatic cholangiocarcinoma; MVI microvascular invasion; TNM tumor-node-metastasis