Recom-. G-5.

National guideline recommendations for the treatment of cancer-related VTE
Recommendation	Grade	Level of evidence	Key references
LMWH is recommended in cases of VTE due to cancer.	Very strong recommendation (I)	A	Kakkos et al.[2] Ortel et al.[9] Kirkilesis et al.[23]
Use of DOAC (apixaban*, edoxaban, rivaroxaban) is recommended for the treatment of cancer-related VTE.	Very strong recommendation (I)	A	Kakkos et al.[2] Ortel et al.[9] Kirkilesis et al.[23] Agnelli et al.[27]Ageno et al.[28]
VTE: Venous thromboembolism; LMWH: Low molecular weight heparin; DOAC: Direct oral anticoagulant; * Apixaban may be preferred primarily in carefully selected patients with gastrointestinal system tumors.