Recom-. G-8.

Recommendation	Grade	Level of evidence	Key references
In the presence of distal DVT, three months treatment is preferred to a shorter treatment.	Very strong recommendation (I)	A	Kirkilesis et al.[51]
DOACs are preferred to LMWH. The other option is VKA.	Very strong recommendation (I)	C	Kakkos et al.[16]
In the presence of symptomatic calf DVT plus cancer, treatment for more than three months is recommended.	Very strong recommendation (I)	C	Galanaud et al.[52]
DVT: Deep vein thrombosis; DOAC: Direct oral anticoagulant; LMWH: Low molecular weight heparin; VKA: Vitamin K antagonist.