Table 3. Factors that may affect the choice of anticoagulant drugs.

Factor	Drug of choice
Cancer Single dose request Reluctance to parenteral therapy Liver disease and coagulopathy Renal insufficiency (creatinine clearance rate <30 mL/min) Coronary artery disease Pregnancy Neutralization possibility Dyspepsia and risk of GIS bleeding	LMWH and DOAC Rivaroxaban, edoxaban, VKA Rivaroxaban, apixaban LMWH VKA VKA, rivaroxaban, apixaban LMWH Standard heparin Apixaban
LMWH: Low molecular weight heparin; DOAC: Direct oral anticoagulant; VKA: Vitamin K antagonist; GIS: Gastrointestinal system.