Fig. 1.

Scatterplots of the E gene sgRNA (A) and gRNA (B) load in the three sample types with different duration of illness (n ​= ​264). Spearman's rank correlation coefficient (r) and P value were attached for each sample type. Sample types were indicated with different colors. Generalized estimating equations were used to fit the dynamics of sgRNA/gRNA load. Violin plot of sgRNA (C) and gRNA (D) load versus the duration of treatment (days). ∗P ​< ​0.05 by Mann-Whitney U test. sgRNA, subgenomic RNA; gRNA, genomic RNA.