TABLE 2.

Seroreactivity in an ELISA for sera of patients harboring HSV-2 isolates with point mutations within the immunodominant region of mgG-2

Patient serum	End point titer
	mgG-2 antigena	mgG-2 peptideb	gG-1 antigenc
448 and 449d	800	400	800
429	400	400	800
2944	3,200	800	3,200
287	200	400	400
216	12,800	6,400	800
3023	100	200	6,400
1915	200	200	800
4530	400	800	400
3089	800	400	—

^aH. pomatia lectin-purified mgG-2. 

^bA 23-mer peptide representing the immunodominant region of mgG-2. 

^cRecombinant gG-1. —, end point titer of less than 50. 

^dTwo isolates from the same patient.