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PCSK9 interacts with GSTP1. (A) Co-immunoprecipitation of PCSK9-binding proteins followed by mass spectrometry identified GSTP1 as a PCSK9-binding protein. (B) The presence of PCSK9 and GSTP1 in the immunoprecipitates was confirmed by Western blot with specific antibodies. (C) Immunofluorescence staining analysis showed that PCSK9 co-localized with GSTP1 in the cytoplasm. (D) The interaction between PCSK9 and GSTP1 was further verified in Huh7 cells.
