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. Author manuscript; available in PMC: 2022 May 9.
Published in final edited form as: Sci Signal. 2021 Nov 9;14(708):eabg2648. doi: 10.1126/scisignal.abg2648

Fig. 8: Summary.

Fig. 8:

Targeting ischemia-induced KCC2 hypofunction with the KCC2 functional enhancer CLP290 rescued refractory neonatal seizures at P7 and mitigated epileptogenesis in same pups at P12.