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. 2021 Sep 20;39(1):msab279. doi: 10.1093/molbev/msab279

Table 1.

Butyrate Production Values from Published Studies of Humans and Nonhuman Primates.

Species Concentration Proportion of SCFA Method Substrates Study Notes
Platyrrhine
Alouatta pigra 1.7–2.8 mM Fecal metabolite concentration NA Amato et al. (2015)
Cercopithecoid
Cercopithecus neglectus 7.53 mM 16.42 mol% In vitro fermentation (12 h) Blended species-specific diet Lambert and Fellner (2012) Captive individuals
Colobus guereza 5.96 mM 10.43 mol% In vitro fermentation (12 h) Blended species-specific diet Lambert and Fellner (2012) Captive individuals
Papio hamadryas 9.04 mM 10.86 mol% In vitro fermentation (12 h) Blended species-specific diet Lambert and Fellner (2012) Captive individuals
Papio hamadryas 17.80 mM 31.43 mol% In vitro fermentation (24 h) Blended species-specific diet McKenney et al. (2014) Captive individuals
Macaca fascicularis 3 mol% Fecal metabolite concentration NA Nagpal et al. (2018) Captive individuals
Macaca mulatta 4.41–4.57 nmol/g Fecal metabolite concentration NA Hasegawa et al. (2018) Captive individuals, juveniles only
Ape
Gorilla gorilla 9.01 mM 13.00 mol% In vitro fermentation (12 h) Blended species-specific diet Lambert and Fellner (2012) Captive individuals
Gorilla gorilla 19.47 mM 28.57 mol% In vitro fermentation (24 h) Blended species-specific diet McKenney et al. (2014) Captive individuals
Pan troglodytes 7.30 mM 9.20 mol% In vitro fermentation (12 h) Blended species-specific diet Lambert and Fellner (2012) Captive individuals
Pan troglodytes 8.94 mM 16.45 mol% In vitro fermentation (24 h) Blended species-specific diet McKenney et al. (2014) Captive individuals
Gorilla gorilla 8.4–12 mol% Fecal metabolite concentration NA Gomez et al. (2015)
Human
 Humans—Industrialized 8–26 mol% In vitro fermentation (24 h) Pectin, gum Arabic, oat bran, wheat bran, and cellulose Bugaut and Bentéjac (1993)
 Humans—Industrialized 3.0–23.7 mM 8.4–13.6 mol% In vitro fermentation (7 days) Amylopectin, pectin, inulin (dahlia), xylan (oat), and inulin (chicory) Duncan et al. (2003)
 Humans—Industrialized 26.1 μmol/ml Cecum metabolite concentration NA Bugaut and Bentéjac (1993)
 Humans—Industrialized 4.36–17.67 mM 7–16 mol% Fecal metabolite concentration NA Duncan et al. (2007)
 Humans—Industrialized 3 mol% Fecal metabolite concentration NA Nagpal et al. (2018)
 Humans—Industrialized 0.675 ± 0.71 μmol/g 16.60 ± 5.2% Fecal metabolite concentration NA Schnorr et al. (2014)
 Humans—Nonindustrialized 0.601 ± 0.43 μmol/g 12.16 ± 4.5% Fecal metabolite concentration NA Schnorr et al. (2014)