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. Author manuscript; available in PMC: 2022 Jul 5.
Published in final edited form as: Chem Soc Rev. 2021 Jul 5;50(13):7436–7495. doi: 10.1039/d0cs01096k

Fig. 39.

Fig. 39

(a) Illustration of the detection mechanism of 135 towards Sirtuin. (b) Time-dependent fluorescence spectra of 135 in the presence of SIRT1. (c) Fluorescence images of cells pre-treated by serum starvation for 36 h, and then 135 for 2 h. C1: 520–560 nm, C2: 620–690 nm, C3: overlap. (b) and (c) are adapted with permission from ref. 241. Copyright 2019 Elsevier.