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. Author manuscript; available in PMC: 2022 Jul 5.
Published in final edited form as: Chem Soc Rev. 2021 Jul 5;50(13):7436–7495. doi: 10.1039/d0cs01096k

Fig. 8.

Fig. 8

(a) Schematic illustration of H2S-triggered release of prodrugs based on the thiolysis of NBD amines. (b) Chemical structure of a prodrug 42 and photo of bacterial growth inhibition for culture plates in the absence or presence of 42 and H2S as indicated inset. (c) Concentration-dependent OD600 values of E. coli in different cultured conditions as indicated inset. (d) Chemical structures of drugs that contain amino groups (highlighted by red *). (b) and (c) are adapted with permission from ref. 90. Copyright 2019 Elsevier.