Table 4.
Comparison of Participants Characteristics Between ABPA-S and ABPA-CB
| ABPA-S (n=41) | ABPA-CB (n=174) | P value | |
|---|---|---|---|
| Age (mean ± SD)2 | 38.31 ± 13.44 | 42.53 ± 13.24 | 0.002 |
| Male, n (%) | 17 (41.5%) | 80 (46.0%) | 0.56 |
| Mucus plugs, n (%) | 2 (4.9%) | 50 (28.7%) | 0.001 |
| Laboratory examination | |||
| Total eosinophil count cell (×10^9/L) (mean ± SD) | 0.98 ± 0.34 | 1.85 ± 0.65 | 0.001 |
| Total IgE level (IU/mL) (mean ± SD) | 4146.34 ± 1723.43 | 4572.32 ± 1366.76 | 0.04 |
| Sp-IgE A. fumigatus | |||
| Grade 1–2 | 14 (34.1%) | 29 (26.7%) | |
| Grade 3–4 | 20 (48.8%) | 116 (66.7%) | |
| Grade 5–6 | 7 (17.1%) | 29 (16.7%) | |
| Spirometry (mean ± SD) | |||
| FVC% | 80.4 ± 10.3 | 78.3 ± 9.8 | 0.03 |
| FEV1% | 65.9 ± 14.2 | 62.3 ± 10.4 | 0.12 |
| FEV1/FVC | 64.2 ± 12.3 | 63.7 ± 14.3 | 0.67 |
| DLCO% | 90.4 ± 9.2 | 82.6 ± 14.5 | 0.005 |
| Clinical outcomes (n=154) | |||
| No. of 2-year follow-up | 30 | 124 | |
| No. of relapses, n (%) | 8 (26.7%) | 67 (54.0%) | 0.007 |
Abbreviations: ABPA-S, ABPA-serum; ABPA-CB, ABPA-central bronchiectasis; Sp-IgE, Aspergillus-specific immunoglobulin E; FEV1, forced expiratory volume in 1s; FVC, forced vital capacity; DLCO, diffusing capacity of the lungs for carbon monoxide; SD, standard deviation.