Table 5.
Comparison of Participants Characteristics Between with or without Asthma
| ABPA without Asthma (n=13) | ABPA with Asthma (n=180) | P value | |
|---|---|---|---|
| Age (mean ± SD) | 49.0 ± 16.8 | 52.5 ± 14.4 | 0.12 |
| Male, n (%) | 6 (46.2%) | 85 (47.2%) | 0.26 |
| Laboratory examination | |||
| Total eosinophil count cell (×10^9/L) (mean ± SD) | 1.54 ± 0.32 | 1.76 ± 0.34 | 0.001 |
| Total IgE level (IU/mL) (mean ± SD) | 2814 ± 1795 | 3527 ± 2730 | 0.22 |
| Sp-IgE A. fumigatus | |||
| Grade 1–2 | 4 (30.8%) | 42 (23.3%) | |
| Grade 3–4 | 6 (46.1%)_ | 106 (58.9%) | |
| Grade 5–6 | 3 (23.1%) | 32 (17.8%) | |
| HRCT findings | |||
| Central Bronchiectasis, n (%) | 13 (100) | 161 (89.44) | 0.02 |
| Mucus plugs, n (%) | 4 (30.77) | 41 (22.78) | 0.21 |
| Spirometry (mean ± SD) | |||
| FVC% | 93.9 ± 13.72 | 79.4 ± 12.82 | 0.001 |
| FEV1% | 90.0 ± 11.19 | 64.8 ± 19.99 | 0.001 |
| FEV1/FVC | 77.6 ± 12.12 | 66.3 ± 16.72 | 0.001 |
| Clinical Outcomes (n = 154) | |||
| No. of 2-year follow-up | 13 | 141 | |
| The mean time to first ABPA exacerbation (mean ± SD), m | 15.38 ± 3.11 | 13.67 ± 2.64 | 0.03 |
Abbreviations: Sp-IgE, Aspergillus-specific immunoglobulin E; FEV1, forced expiratory volume in 1s; FVC, forced vital capacity; DLCO, diffusing capacity of the lungs for carbon monoxide; SD, standard deviation.