Table 7.
Univariate Analysis of the Factors Associated with Acute ABPA Exacerbation for 154 Patients After 2-Year Follow-Up
| Acute Exacerbation of ABPA (n=75) | Non-Acute Exacerbation of ABPA (n=79) | P value | |
|---|---|---|---|
| Age (mean ± SD) | 53.42 ± 15.78 | 45.12 ± 13.64 | 0.01 |
| Male, n (%) | 42 (56%) | 37 (46.8%) | 0.49 |
| Haemoptysis, n (%) | 10 (13.33) | 6 (7.59) | 0.02 |
| Mucus plugs, n (%) | 33 (44.00) | 20 (25.31) | 0.01 |
| Coexisting Asthma, n (%) | 70 (93.33) | 71 (89.87) | 0.2 |
| Duration of asthma (year) (mean ± SD) | 7.31 ± 3.32 | 5.53 ± 2.31 | 0.01 |
| Duration of misdiagnosis (year) (mean±SD) | 5.81 ± 1.33 | 4.21 ± 1.41 | 0.01 |
| Total eosinophil count cell (×10^9/L) (mean ± SD) | 1.87 ± 0.54 | 1.52 ± 0.64 | 0.01 |
| Total IgE level (IU/mL) (mean ± SD) | 3850.54 ± 769.23 | 4428.54 ± 670.06 | 0.5 |
| HRCT findings | |||
| Mucus plugs, n (%) | 37 (49.33) | 19 (24.05) | 0.01 |
| Spirometry (mean ± SD) | |||
| FEV1% | 43.21 ± 9.13 | 69.51 ± 14.74 | 0.01 |
| FVC% | 73.93 ± 10.12 | 78.21 ± 18.64 | 0.02 |
| FEV1/FVC | 57.13 ± 14.75 | 65.61 ± 13.45 | 0.01 |
| DLCO% | 81.21 ± 8.91 | 83.41 ± 11.25 | 0.05 |
Abbreviations: IgE, immunoglobulin E; FEV1, forced expiratory volume in 1s; FVC, forced vital capacity; DLCO, diffusing capacity of the lungs for carbon monoxide; SD, standard deviation.