TABLE 1.

Inhibition constants (K_I, k _inact, k _2nd) of the compounds 4 and 5a–k for S. aureus SrtA; n. i. = <20% inhibition at 100 µM.

Cpd.	Structure	KI [µM]	k inact [s−1]	k 2nd [M−1min−1]
4		47.1 ± 15.7	0.00065 ± 0.00007	870 ± 170
5a		57.6 ± 3.55	0.00774 ± 0.00007	8,088 ± 464
5b		42.37 ± 4.62	0.00082 ± 0.00004	1,175 ± 67
5c		n. i.
5d		n. i.
5f		n. i.
5g		n. i.
5h		n. i.
5i		n. i.
5k		n. i.