Table 1.
Activity of different fractions obtained from T. diffusa.
| % recovery | Hepatoprotection, AST (UI/L) | Cytotoxic activity, CC50 μg/mL | |
|---|---|---|---|
| ME | 12.08 | 95.33 ± 11.1 | 49.73 ± 5.03 |
| CME | 6.04 | 82.00 ± 6.08 | >500 |
| FrVLC | 1.98 | 41.33 ± 6.50 | >500 |
| FrMF | 0.47 | 32.33 ± 5.13 | >500 |
| Hepatodamianol | 20.23 ± 3.67 | >500 | |
| Silibinin | 81.33 ± 6.02 | ||
| Doxorubicin | 3.12 ± 0.23 |
Recovery was calculated based on the dry plant. Hepatoprotection model in vitro: HepG2 cells; CCl4 0.4% as a damage agent, cells + CCl4: AST 111.33 ± 3.51, cells without CCl4: AST 0.66 ± 0.57. Cytotoxicity was assessed in Vero cells; n = 3.