Table 2.
Multivariate Cox's proportional hazard regression model for the association between postprandial TG variability and eGFR decline (primary endpoint).
| HR [95% CI] p value | SD ≥ 37 | Adj − SD ≥ 34 | MMD ≥ 95 |
|---|---|---|---|
| Model 1 | 1.69 [1.15-2.52] 0.0076 | 1.73 [1.18-2.57] 0.0052 | 1.64 [1.12-2.43] 0.0110 |
| Model 2 | 1.61 [1.05-2.51] 0.0276 | 1.66 [1.09-2.58] 0.0193 | 1.56 [1.02-2.41] 0.0388 |
| Model 3 | 1.58 [1.03-2.46] 0.0351 | 1.63 [1.06-2.52] 0.0251 | 1.54 [1.01-2.37] 0.0463 |
| Model 4 | 1.62 [1.05-2.53] 0.0284 | 1.66 [1.08-2.58] 0.0218 | 1.59 [1.04-2.47] 0.0340 |
Model 1: adjusted for age, sex, and BMI. Model 2: adjusted for age, sex, BMI, and mean TG. Model 3: adjusted for age, sex, BMI, mean TG, baseline eGFR, and proteinuria. Model 4: adjusted for age, sex, BMI, mean TG, baseline eGFR, proteinuria, HbA1c, smoking, hypertension, and fibrates intake. TG: triglyceride; SD: standard deviation; Adj-SD: adjusted SD; MMD: maximum minus minimum difference; HR: hazard ratio; 95% CI: 95% confidence intervals; BMI: body mass index; eGFR: estimated glomerular filtration rate; HbA1c: glycated hemoglobin.