Fig. 2.

Higher WBP2 protein expression is associated with higher WBP2 mRNA and copy number alterations, as well as breast cancer progression in TCGA BRCA (A) TCGA BRCA samples were arranged according to WBP2 protein z‐scores and stratified into two groups according to their median (vertical lines). The two groups are termed as ‘WBP2p_low’ (green triangle) and ‘WBP2p_high’ (red dot). (B) Comparison of (i) WBP2 protein z‐scores and (ii) log₂(WBP2 mRNA expression) ***P < 0.001 (unpaired t‐test) (C) Percentage of samples in each stage of American Joint Committee on Cancer (AJCC) stage code was computed and plotted on a bar char. Chi‐squared test was performed to determine the statistical significance. (D) Workflow to filter and select the DEGs in WBP2p_high and WBP2p_low groups. The significance of DEGs in the two groups was derived from Student's t‐test.