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. 2021 Oct 31;16(2):333–346. doi: 10.1002/1878-0261.13113

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© 2021 The Authors. Molecular Oncology published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Fig. 4 — Number of disseminated tumor cells with copy number alterations in chromosomal regions where known oncogenes and tumor suppressor genes for head and neck squamous cell carcinoma (HNSCC) are located. (A) Number of bone marrow‐derived (BM) and lymph node‐derived (LN) cells (y‐axis) with amplifications in HNSCC oncogenes (A) or losses in tumor suppressors (B) (Tables 3 and 4). Each point corresponds to a gene locus and the most frequently amplified, and deleted gene loci are labeled. P‐values are calculated using a paired Wilcoxon rank‐sum test.