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. 2022 Jan 4;15:785620. doi: 10.3389/fnhum.2021.785620

Figure 2.

Figure 2

Two Patterns of CL-taVNS. (A) workflow of instantaneous CL-taVNS. The system will be activated as soon as the On Biomarker is identified and deactivated when the Off Biomarker is determined by the identifier simultaneously. (B) Workflow of continuous CL-taVNS. The biofeedback is used to control stimulation parameters of taVNS (pulse width, current intensity, frequency, On-Off time, and stimulating duration) to adhere to momentary therapeutic needs. The biofeedback can also be used for temporal synchronization of the applied stimuli with inner body rhythms to interfere constructively with the dynamics of the body. CL-taVNS: Closed-loop transcutaneous auricular vagal nerve stimulation.