TABLE 2.
Fifty-one human genes related to the etiology and prognosis of FSGS.
| Genes | Official full name |
|---|---|
| ACTN4 | Actinin alpha 4 |
| ANLN | Anillin actin binding protein |
| APOL1 | Apolipoprotein L1 |
| CD2AP | CD2 associated protein |
| CLCN5 | Chloride voltage-gated channel 5 |
| CLCNKB | Chloride voltage-gated channel Kb |
| COQ6 | Coenzyme Q6, monooxygenase |
| COQ8B | Coenzyme Q8B |
| CRB2 | Crumbs cell polarity complex component 2 |
| G6PC | Glucose-6-phosphatase catalytic subunit |
| INF2 | Inverted formin 2 |
| ITGA3 | Integrin subunit alpha 3 |
| JAG1 | Jagged canonical Notch ligand 1 |
| MT-CO1 | Mitochondrially encoded cytochrome c oxidase I |
| MT-CO2 | Mitochondrially encoded cytochrome c oxidase II |
| MT-CO3 | Mitochondrially encoded cytochrome c oxidase III |
| MT-ND1 | Mitochondrially encoded NADH: ubiquinone oxidoreductase core subunit 1 |
| MT-ND4 | Mitochondrially encoded NADH: ubiquinone oxidoreductase core subunit 4 |
| MT-ND5 | Mitochondrially encoded NADH: ubiquinone oxidoreductase core subunit 5 |
| MT-ND6 | Mitochondrially encoded NADH: ubiquinone oxidoreductase core subunit 6 |
| MT-TF | Mitochondrially encoded tRNA-Phe (UUU/C) |
| MT-TH | Mitochondrially encoded tRNA-His (CAU/C) |
| MT-TL1 | Mitochondrially encoded tRNA-Leu (UUA/G) 1 |
| MT-TQ | Mitochondrially encoded tRNA-Gln (CAA/G) |
| MT-TS1 | Mitochondrially encoded tRNA-Ser (UCN) 1 |
| MT-TS2 | Mitochondrially encoded tRNA-Ser (AGU/C) 2 |
| MT-TW | Mitochondrially encoded tRNA-Trp (UGA/G) |
| MYO1E | Myosin IE |
| NARS2 | Asparaginyl-tRNA synthetase 2, mitochondrial |
| NPHS2 | NPHS2 stomatin family member, podocin |
| NUP107 | Nucleoporin 107 |
| NUP133 | Nucleoporin 133 |
| NUP160 | Nucleoporin 160 |
| NUP205 | Nucleoporin 205 |
| NUP85 | Nucleoporin 85 |
| NUP93 | Nucleoporin 93 |
| PAX2 | Paired box 2 |
| PLCE1 | Phospholipase C epsilon 1 |
| PTPRO | Protein tyrosine phosphatase receptor type O |
| REN | Renin |
| SCARB2 | Scavenger receptor class B member 2 |
| SEC61A1 | SEC61 translocon subunit alpha 1 |
| SGPL1 | Sphingosine-1-phosphate lyase 1 |
| SLC12A3 | Solute carrier family 12 member 3 |
| SLC37A4 | Solute carrier family 37 member 4 |
| SMARCAL1 | SWI/SNF related, Matrix associated, Actin dependent regulator of chromatin, Subfamily a like 1 |
| TBC1D8B | TBC1 domain family member 8B |
| TRPC6 | Transient receptor potential cation channel subfamily C member 6 |
| VPS33A | VPS33A core subunit of CORVET and HOPS complexes |
| WDR73 | WD repeat domain 73 |
| WT1 | WT1 transcription factor |