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. 2022 Jan 4;11:798052. doi: 10.3389/fcimb.2021.798052

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Copyright © 2022 Wan, Wang, Zhong, Chen, Han, Liu, Zhao, Lv, Hou, Yi and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of LSE administration on intestinal microbiota inflammatory in DSS-induced colitis mice. (A) A Venn diagram showing the overlap of the OTUs identified in the intestinal microbiota among the three groups. (B) PCoA plot of the gut microbiota based on weighted UniFrac distance. (C) The α-diversity of each group. (D) The abundance of Firmicutes and Bacteroidetes and Firmicutes/Bacteroidetes ratio at phylum levels. Data are presented as mean ± SEM, n = 8. * P < 0.05 and ** P < 0.01 vs. the CON+DSS group, ^†P < 0.05 vs. the CON group.