Table 5.

Associations with cumulative 5-year incidence and progression of age-related macular degeneration (AMD) in the Gutenberg Health Study estimated using robust Poisson regression; baseline parameters were included

	Cumulative 5-year incidence of AMD			Cumulative 5-year progression of AMD
	RR	95% CI	p	RR	95% CI	p
Sex (women)	0.91	0.60; 1.38	0.66	0.90	0.59; 1.39	0.63
Age [10 y]	2.30	1.83; 2.80	< 0.0001	1.60	1.22; 2.12	< 0.001
Smoking	1.36	0.84; 2.20	0.21	0.95	0.53; 1.69	0.86
Alcohol consumption (> 10 g/d for women and > 20 g/d for men)	1.07	0.73; 1.58	0.72	0.84	0.56; 1.27	0.42
BMI [kg/m2]	1.05	1.01; 1.09	0.017	1.02	0.97; 1.07	0.37
HbA1c [%]	1.09	0.83; 1.44	0.54	1.24	0.99; 1.56	0.06
LDL [mg/dl]	1.00	1.00; 1.01	0.62	1.00	1.00; 1.01	0.79
HDL [mg/dl]	1.01	0.99; 1.02	0.32	1.01	0.99; 1.02	0.34
Log (triglycerides [mg/dl])	0.89	0.53; 1.51	0.67	0.82	0.50; 1.33	0.42
Mean arterial blood pressure [mmHg]	0.99	0.97; 1.01	0.20	1.00	0.99; 1.02	0.67
Spherical equivalent [dpt]	0.97	0.90; 1.05	0.48	1.07	0.99; 1.16	0.11
Pseudophakia	2.52	1.41; 4.53	0.0019	0.86	0.42; 1.77	0.67
Family history of AMD	1.58	0.81; 3.09	0.18	1.10	0.57; 2.14	0.77

AMD, age-related macular degeneration; RR, risk ratio; 95% CI, 95% confidence interval