Skip to main content
. 2022 Jan 4;12:790347. doi: 10.3389/fphys.2021.790347

TABLE 4.

Hazard ratios of different BMR categories for all-cause mortality grouped by age and sex.

Variables Event, n (%) Crude model
Model I
Model II
HR (95%CI) P-value HR (95%CI) P-value HR (95%CI) P-value
Male

Age < 60 years
BMR (kcal/day)
 Per SD increase 71 (3.15%) 0.83 (0.66, 1.05) 0.114 0.83 (0.66, 1.05) 0.121 0.95 (0.73, 1.24) 0.713
Quartiles of BMR
  Q1 [843, 1112] 3 (2.11%) Ref Ref Ref
  Q2 [1120, 1219] 12 (5.22%) 2.38 (0.67, 8.42) 0.180 2.33 (0.66, 8.25) 0.191 2.23 (0.62, 8.04) 0.222
  Q3 [1220, 1367] 20 (4.77%) 2.54 (0.75, 8.55) 0.133 2.20 (0.65, 7.41) 0.206 2.36 (0.69, 8.08) 0.170
  Q4 [1368, 1789] 36 (2.46%) 1.36 (0.42, 4.41) 0.613 1.25 (0.38, 4.05) 0.716 1.55 (0.47, 5.13) 0.474
 P for trend 0.193 0.143 0.634
Age ≥ 60 years
BMR (kcal/day)
 Per SD increase 407 (15.65%) 0.62 (0.56, 0.69) <0.001 0.74 (0.66, 0.83) <0.001 0.80 (0.70, 0.91) <0.001
Quartiles of BMR
  Q1 [848, 1115] 75 (27.68%) Ref Ref Ref
  Q2 [1116, 1218] 98 (20.42%) 0.69 (0.51, 0.93) 0.015 0.79 (0.58, 1.07) 0.124 0.78 (0.58, 1.07) 0.122
  Q3 [1220, 1367] 129 (16.02%) 0.53 (0.40, 0.71) <0.001 0.68 (0.51, 0.90) 0.008 0.71 (0.53, 0.95) 0.022
  Q4 [1368, 1788] 105 (10.05%) 0.32 (0.24, 0.43) <0.001 0.49 (0.36, 0.66) <0.001 0.60 (0.43, 0.84) 0.003
 P for trend <0.001 <0.001 0.004

Female

Age < 60 years
BMR (kcal/day)
 Per SD increase 55 (1.41%) 0.84 (0.56, 1.28) 0.423 0.84 (0.56, 1.27) 0.411 0.91 (0.55, 1.51) 0.723
Quartiles of BMR
  Q1 [797, 1115] 15 (1.41%) Ref Ref Ref
  Q2 [1116, 1219] 21 (1.53%) 1.05 (0.54, 2.04) 0.880 1.04 (0.54, 2.03) 0.898 1.22 (0.61, 2.44) 0.571
  Q3 [1220, 1367] 16 (1.41%) 0.99 (0.49, 1.99) 0.967 0.97 (0.48, 1.97) 0.943 1.10 (0.49, 2.49) 0.811
  Q4 [1368, 1771] 3 (0.85%) 0.58 (0.17, 2.01) 0.394 0.57 (0.16, 1.96) 0.369 0.70 (0.17, 2.86) 0.624
 P for trend 0.473 0.441 0.755
Age ≥ 60 years
BMR (kcal/day)
 Per SD increase 55 (1.41%) 0.74 (0.63, 0.87) <0.001 0.97 (0.83, 1.13) 0.712 1.05 (0.89, 1.25) 0.550
Quartiles of BMR
  Q1 [787, 1115] 152 (9.89%) Ref Ref Ref
  Q2 [1116, 1219] 66 (6.84%) 0.68 (0.51, 0.91) 0.010 0.92 (0.69, 1.24) 0.600 0.97 (0.71, 1.33) 0.844
  Q3 [1220, 1367] 48 (7.25%) 0.72 (0.52, 1.00) 0.052 1.06 (0.76, 1.48) 0.740 1.23 (0.85, 1.79) 0.268
  Q4 [1368, 1761] 10 (5.46%) 0.54 (0.28, 1.02) 0.058 0.71 (0.37, 1.34) 0.287 0.81 (0.42, 1.56) 0.525
 P for trend 0.006 0.531 0.911

Abbreviations: BMR, basal metabolic rate; Ref, reference; HR, hazard ratio; CI, confidence interval; SD, standard deviation.

Model I adjusted for age.

Model II adjusted for age, SBP, DBP, BMI, education level, current smokers and drinkers, history of stroke and physical activity levels.