TABLE 4.
Hazard ratios of different BMR categories for all-cause mortality grouped by age and sex.
Variables | Event, n (%) | Crude model |
Model I |
Model II |
|||||
HR (95%CI) | P-value | HR (95%CI) | P-value | HR (95%CI) | P-value | ||||
Male | |||||||||
| |||||||||
Age < 60 years | |||||||||
BMR (kcal/day) | |||||||||
Per SD increase | 71 (3.15%) | 0.83 (0.66, 1.05) | 0.114 | 0.83 (0.66, 1.05) | 0.121 | 0.95 (0.73, 1.24) | 0.713 | ||
Quartiles of BMR | |||||||||
Q1 [843, 1112] | 3 (2.11%) | Ref | Ref | Ref | |||||
Q2 [1120, 1219] | 12 (5.22%) | 2.38 (0.67, 8.42) | 0.180 | 2.33 (0.66, 8.25) | 0.191 | 2.23 (0.62, 8.04) | 0.222 | ||
Q3 [1220, 1367] | 20 (4.77%) | 2.54 (0.75, 8.55) | 0.133 | 2.20 (0.65, 7.41) | 0.206 | 2.36 (0.69, 8.08) | 0.170 | ||
Q4 [1368, 1789] | 36 (2.46%) | 1.36 (0.42, 4.41) | 0.613 | 1.25 (0.38, 4.05) | 0.716 | 1.55 (0.47, 5.13) | 0.474 | ||
P for trend | 0.193 | 0.143 | 0.634 | ||||||
Age ≥ 60 years | |||||||||
BMR (kcal/day) | |||||||||
Per SD increase | 407 (15.65%) | 0.62 (0.56, 0.69) | <0.001 | 0.74 (0.66, 0.83) | <0.001 | 0.80 (0.70, 0.91) | <0.001 | ||
Quartiles of BMR | |||||||||
Q1 [848, 1115] | 75 (27.68%) | Ref | Ref | Ref | |||||
Q2 [1116, 1218] | 98 (20.42%) | 0.69 (0.51, 0.93) | 0.015 | 0.79 (0.58, 1.07) | 0.124 | 0.78 (0.58, 1.07) | 0.122 | ||
Q3 [1220, 1367] | 129 (16.02%) | 0.53 (0.40, 0.71) | <0.001 | 0.68 (0.51, 0.90) | 0.008 | 0.71 (0.53, 0.95) | 0.022 | ||
Q4 [1368, 1788] | 105 (10.05%) | 0.32 (0.24, 0.43) | <0.001 | 0.49 (0.36, 0.66) | <0.001 | 0.60 (0.43, 0.84) | 0.003 | ||
P for trend | <0.001 | <0.001 | 0.004 | ||||||
| |||||||||
Female | |||||||||
| |||||||||
Age < 60 years | |||||||||
BMR (kcal/day) | |||||||||
Per SD increase | 55 (1.41%) | 0.84 (0.56, 1.28) | 0.423 | 0.84 (0.56, 1.27) | 0.411 | 0.91 (0.55, 1.51) | 0.723 | ||
Quartiles of BMR | |||||||||
Q1 [797, 1115] | 15 (1.41%) | Ref | Ref | Ref | |||||
Q2 [1116, 1219] | 21 (1.53%) | 1.05 (0.54, 2.04) | 0.880 | 1.04 (0.54, 2.03) | 0.898 | 1.22 (0.61, 2.44) | 0.571 | ||
Q3 [1220, 1367] | 16 (1.41%) | 0.99 (0.49, 1.99) | 0.967 | 0.97 (0.48, 1.97) | 0.943 | 1.10 (0.49, 2.49) | 0.811 | ||
Q4 [1368, 1771] | 3 (0.85%) | 0.58 (0.17, 2.01) | 0.394 | 0.57 (0.16, 1.96) | 0.369 | 0.70 (0.17, 2.86) | 0.624 | ||
P for trend | 0.473 | 0.441 | 0.755 | ||||||
Age ≥ 60 years | |||||||||
BMR (kcal/day) | |||||||||
Per SD increase | 55 (1.41%) | 0.74 (0.63, 0.87) | <0.001 | 0.97 (0.83, 1.13) | 0.712 | 1.05 (0.89, 1.25) | 0.550 | ||
Quartiles of BMR | |||||||||
Q1 [787, 1115] | 152 (9.89%) | Ref | Ref | Ref | |||||
Q2 [1116, 1219] | 66 (6.84%) | 0.68 (0.51, 0.91) | 0.010 | 0.92 (0.69, 1.24) | 0.600 | 0.97 (0.71, 1.33) | 0.844 | ||
Q3 [1220, 1367] | 48 (7.25%) | 0.72 (0.52, 1.00) | 0.052 | 1.06 (0.76, 1.48) | 0.740 | 1.23 (0.85, 1.79) | 0.268 | ||
Q4 [1368, 1761] | 10 (5.46%) | 0.54 (0.28, 1.02) | 0.058 | 0.71 (0.37, 1.34) | 0.287 | 0.81 (0.42, 1.56) | 0.525 | ||
P for trend | 0.006 | 0.531 | 0.911 |
Abbreviations: BMR, basal metabolic rate; Ref, reference; HR, hazard ratio; CI, confidence interval; SD, standard deviation.
Model I adjusted for age.
Model II adjusted for age, SBP, DBP, BMI, education level, current smokers and drinkers, history of stroke and physical activity levels.