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. 2022 Jan 4;11:787814. doi: 10.3389/fonc.2021.787814

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Copyright © 2022 Zheng, Sun, Yi, Zhang, Wang, Lan, Zhang, Xian and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The correlation among 5 pathways dysregulated in MM patients and their prognostic significances. (A) Heatmap of the correlation among 5 cancer-related signaling pathways using Pearson correlation coefficients. (B) The comparison of mRNA expression level of YAP1/MYC/MTOR/ERBB2/VEGFA/TAZ in 2 MM groups. Results are shown as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, based on the Student’s t-test. (C) Kaplan–Meier survival curves comparing the overall survival in MM cases with high or low expression of YAP1/MYC in the GSE24080 dataset. (D) Kaplan–Meier survival curves comparing the overall survival in MM cases with differential expression levels of YAP1 and MYC in the GSE24080 dataset. ns, not significant.