Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jan 4;11:787814. doi: 10.3389/fonc.2021.787814

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Zheng, Sun, Yi, Zhang, Wang, Lan, Zhang, Xian and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Dysregulated DNA repair process and metabolic reprogramming in Group 1 MM facilitated extramedullary invasion. (A) tSNE plots of 447 single-cell transcriptome data of primary and extramedullary MM samples based on the GSE106218 dataset. (B) The distribution and intensity of the expression of MYC/PARP1/LDHA/IDH3A on tSNE plots. (C) Pseudo time analysis of 447 single-cell transcriptome data via Monocle algorithm. Arrows indicated evolutionary directions. (D) The distribution and intensity of the expression of MYC/PARP1/LDHA/IDH3A on Monocle plots. (E) The expression intensity of MYC/PARP1/LDHA/IDH3A along pseudo time axis.