Fig. 1. o-Phosphinophenolate as photocatalyst for C–F functionalization of –CF₃.

a Design of a system that uses o-phosphinophenolate (PO^–) as a photoredox catalyst. b Generation of –CF₂• radicals from –CF₃ groups using PO^–. c Hypothesized photocatalytic cycles for defluoroalkylation and hydrodefluorination. hv light, SET single electron transfer, HAT hydrogen atom transfer.