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. 2021 Oct 19;70(1):79–85. doi: 10.3164/jcbn.21-79

Table 5.

Univariate and multivariate analysis of the development of dyspepsia

Univariate analysis Multivariate analysis
Parameter Odds ratio 95% CI p value Odds ratio 95% CI p value
Age 0.979 0.952–1.007 0.145
Sex (male) 0.317 0.121–0.830 0.014 0.333 0.117–0.948 0.039
Body mass index >22 (kg/m2) 0.898 0.527–1.528 0.691
Smoking 1.164 0.723–1.875 0.532
Alcohol consumption 1.15 0.697–1.895 0.585
Helicobacter pylori infection 1.352 0.845–2.162 0.207
Disease
 Hypertension 0.695 0.280–1.722 0.43
 Hyperlipidemia 2.498 0.411–15.185 0.304
 Diabetes mellitus 0.923 0.102–8.366 0.943
 Heart diseases 1.4 0.364–5.389 0.623
 Cancer 0.944 0.986–1.002 0.461
Endoscopic disease
 Hiatal hernia 0.937 0.576–1.522 0.791
 Short-segment Barrett’s esophagus 0.602 0.376–0.964 0.034 0.569 0.349–0.928 0.024
 Gastroesophageal reflux diseases 1.146 0.644–2.040 0.643
 Gastric ulcer 1.161 0.415–2.270 0.773
 Gastric ulcer scar 0.209 0.027–1.589 0.13 0.119 0.014–1.036 0.054
 Duodenal ulcer 1.238 0.245–6.239 0.796
 Duodenal ulcer scar 1.243 0.391–3.952 0.721
Endoscopic Kyoto classification
 Atrophy 0.782 0.556–1.098 0.155 0.868 0.568–1.326 0.513
 Intestinal metaplasia 0.616 0.192–1.975 0.415
 Enlarged folds 0.87 0.441–1.714 0.687
 Nodularity 0.4 0.066–2.433 0.32
 Diffuse redness 0.268 0.513–1.331 0.433
 Total scores 0.907 0.767–1.072 0.254
Endoscopic finding
 Regular arrangement of collecting venules 0.835 0.522–1.338 0.454
 Bile reflux 0.923 0.102–8.366 0.943
 Map-like redness
 Xanthoma 0.976 0.959–1.992 0.537
 Hematin 0.607 0.247–1.493 0.273
 Red streak 1.264 0.763–2.094 0.362
 Fundic gland polyp 3.173 1.387–7.260 0.006 3.413 1.430–8.142 0.006
 Hyperplastic polyp 0.523 0.063–4.305 0.54
 Mucosal swelling 0.626 0.211–1.860 0.395
 Patchy redness 0.985 0.972–0.998 0.242
 Sticky mucous 0.487 0.167–1.423 0.18 0.199 0.203–2.408 0.571
 Antral erosion 1.279 0.676–2.421 0.448
 Raised erosion 1.513 0.570–4.021 0.403
 Spotty redness 0.89 0.492–1.607 0.698
 Multiple white and flat elevated lesion 1.022 0.450–2.320 0.959