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. 2022 Jan 4;12:769948. doi: 10.3389/fphys.2021.769948

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Copyright © 2022 Mehta, Sherbansky, Kamer, Carare, Butler, Rusinek, Chiang, Li, Strauss, Saint-Louis, Theise, Suss, Blennow, Kaplitt and de Leon.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Structural depiction of CSF flow through the cribriform plate of a mouse model from Norwood Et. Al. (PMID: 31063132). (A) Schematic diagram of anticipated egress from neural tissue into nasal epithelium. (B) Sagittal midline section following injection of EB into cisterna magna. (C) Decalcified spinal column after EB injection into cisterna magna. (D) Visualization of the area enclosed by pink box in (A) depicting contrast movement across the cribriform plate. (E) EB dye localization into deep cervical lymph nodes marked by purple arrows following injection at cisterna magna.