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. 2022 Jan 4;12:769948. doi: 10.3389/fphys.2021.769948

Table 1.

Comparative analysis of olfactory pathway.

Species Study Approximate % of CSF drained through olfactory route Methodology of CSF Tracing Duration of Observation
Sheep Boulton et al., 1997 >50% Intraventricular injection of Human Serum Albumin 6 h
Silver et al., 2002 >50% Intercranial Pressure calculation following CP blockage 300 s
Rats Boulton et al., 1999 40–50% Intraventricular injection of Human Serum Albumin 6 h
Rabbits Bradbury et al., 1981 40–50% Intraventricular injection of radioiodinated albumin 6 h
Dogs Sokołowski et al., 2018 10% Volumetric analysis of the rostral cranial fossa N/A

Synthesized comparison of proportional CSF egress occurring by means of an olfactory drainage route as quantified by Bradbury et al., 1981, Boulton et al., 1997, 1999, Silver et al., 2002 and Sokołowski et al., 2018.