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. 2021 Dec 16;109(1):50–65. doi: 10.1016/j.ajhg.2021.11.017

Figure 2.

Figure 2

Sharing of eQTLs between Indonesian and European populations

(A) Overlap of permutation-significant (FDR-p < 0.1) eGenes between Indonesia and three European eQTL cohorts.

(B) Pairwise sharing of eQTLs between the datasets across all tested SNP-gene pairs.

(C) Minor allele frequencies of shared and Indonesia-specific eSNPs in Indonesia and the 1000 Genomes European super-population. MAFs are reported relative to the minor allele in Indonesia.

(D) Absolute effect sizes of the shared and Indonesia-specific eQTLs. In (C) and (D), ANOVA p values and t test p values between Indonesia and the European datasets are indicated.

(E) An example of a colocalized gene, RSU1.

(F) An example of an Indonesia-specific eQTL for the gene NRAS. In (E) and (F), −log10(p values) for Indonesia are indicated in blue and for the European datasets are indicated in gray.