. 2021 Aug 27;107(2):e836–e851. doi: 10.1210/clinem/dgab630

Table 3.

Age- and BMI SD score–adjusted correlation analyses between MSCA1/CD36 and obesity-related adipose tissue and serum parameters

	MSCA1 mRNA in SVF cells^a			MSCA1 mRNA in adipocytes^a			CD36 mRNA in SVF cells^a			CD36 mRNA in adipocytes^a
	n	R_adj	P_a	n	R_adj	P_adj	n	R_adj	P_adj	n	R_adj	P_adj
AT composition
Adipocyte diameter, µm	76	0.330	0.004	76	0.206	0.079	74	0.072	0.549	76	0.013	0.913
Total adipocyte number × 109^a	52	−0.223	0.119	52	−0.133	0.356	50	−0.129	0.389	52	0.345	0.014
Isolated adipocytes per g AT × 106^a	77	−0.157	0.177	77	−0.138	0.239	75	0.039	0.742	77	0.217	0.061
Isolated SVF cells per g AT × 105^a	57	0.047	0.735	57	0.228	0.094	56	−0.202	0.14	57	0.014	0.919
AT inflammation
Macrophages per 100 adipocytes^a	108	0.137	0.161	108	0.100	0.310	105	−0.119	0.232	108	−0.070	0.476
CLS^a	108	0.032	0.745	108	0.174	0.075	105	−0.005	0.959	108	−0.081	0.407
hs-CRP, mg/L^a	112	0.381	<0.001	112	0.266	0.005	108	−0.038	0.698	112	−0.007	0.941
TNF-α, pg/mL^a	105	0.056	0.797	105	−0.064	0.521	101	0.114	0.262	105	0.114	0.251
Adipokines and HOMA IR
Adiponectin, mg/L^a	109	−0.080	0.414	109	−0.138	0.157	105	0.072	0.472	109	0.091	0.349
Leptin, ng/mL^a	107	0.098	0.319	107	0.212	0.030	104	−0.152	0.128	107	0.217	0.026
HOMA IR^a	111	0.093	0.335	111	0.069	0.474	107	−0.197	0.045	111	0.015	0.879
AT functional parameters
Doubling time of native cells from the SVF, h^a	51	0.133	0.362	51	0.035	0.811	50	0.207	0.159	51	−0.037	0.802
Growth rate of proliferating native SVF cells^a	45	−0.061	0.699	45	−0.301	0.050	44	−0.089	0.576	45	0.038	0.808
Generation time of proliferating native SVF	45	0.014	0.932	45	0.336	0.028	44	0.024	0.879	45	−0.098	0.533
Differentiation of native cells from the SVF, %	48	−0.079	0.601	48	−0.255	0.088	47	0.177	0.244	48	0.025	0.870
Basal lipolysis of adipocytes	29	−0.370	0.057	29	−0.361	0.064	28	0.041	0.844	29	0.126	0.532
Isoproterenol-stimulated lipolysis of adipocytes	30	−0.417	0.027	30	−0.069	0.727	29	−0.003	0.990	30	0.182	0.354

R indicates the Pearson correlation coefficient. Significant P-values are indicated in bold. R_adj, and P_adj analyses are adjusted for age and BMI SDS.

Abbreviations: AT, adipose tissue; BMI, body mass index; CLS, crown-like structure; HOMA IR, homeostatic model assessment-insulin resistance; hs-CRP, high-sensitivity C-reactive protein; SVF, stromal vascular fraction; TNF-α, tumor necrosis factor α; SDS, SD score.

^aStatistical analysis was performed for log-transformed parameters.