Table 3.
Multivariate-adjusted logistic regression analyses of associations between follicle-stimulating hormone (FSH) levels and sarcopenia, severe sarcopenia, and individual sarcopenia components.
|
Prevalence (%, n) |
Crude model | P | Adjusted modela | P | |
|---|---|---|---|---|---|
| Sarcopenia | |||||
| Higher-FSH | 21.8 (39)* | 1.00 | 1.00 | ||
| Lower-FSH | 13.8 (25) | 0.575 (0.331–0.999) | 0.049 | 0.511 (0.178, 1.467) |
0.212 |
| Severe sarcopenia | |||||
| Higher-FSH | 19.6 (35) | 1.00 | 1.00 | ||
| Lower-FSH | 12.7 (23) | 0.599 (0.338–1.062) | 0.079 | 0.400 (0.136–1.175) | 0.096 |
| Low calf circumference | |||||
| Higher-FSH | 25.1 (45)* | 1.00 | 1.00 | ||
| Lower-FSH | 14.9 (27) | 0.522 (0.307–0.887) | 0.016 | 0.308 (0.109, 0.868) |
0.026 |
| Low handgrip strength | |||||
| Higher-FSH | 84.4 (151)** | 1.00 | 1.00 | ||
| Lower-FSH | 65.7 (119) | 0.386 (0.235–0.636) | <0.001 | 0.390 (0.151,1.005) | 0.051 |
| Low physical performance | |||||
| Higher-FSH | 59.8 (108) | 1.00 | 1.00 | ||
| Lower-FSH | 58.0 (105) | 0.930 (0.611–1.415) | 0.734 | 0.717 (0.305,1.685) | 0.446 |
Data were a proportion with a number for categorical variables and odds ratios (95% confidence interval). Low calf circumference: calf circumference <31 cm; Low handgrip strength: handgrip strength <27 kg; Low physical performance: 4-meter gait speed ≤ 0.8 m/s. All models constructed by logistic regression analysis: a: adjusted for age, waist circumference, education, exercise, LH, E2, TT, TG, LDL-C, 25(OH)D, albumin, FT3, and hsCRP.
*
P < 0.05,
**
P < 0.01, Lower-FSH group vs. Higher-FSH group.