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. 2022 Jan 4;8:797647. doi: 10.3389/fmed.2021.797647

Figure 1.

Figure 1

Dexmedetomidine start day from time of intubation and multivariable Cox regression assessing 28-day mortality from time of intubation accounting for time-varying exposure to dexmedetomidine. (A) Time to dexmedetomidine use from time of intubation. Day 0 includes patients already on dexmedetomidine prior to intubation. (B) Multivariable Cox regression assessing 28-day mortality from time of intubation accounting for dexmedetomidine as a time-varying covariate. Cut-off for dexmedetomidine start time from intubation included early start time (<3.4 days), later start time (>3.4 days), and all patients in the dexmedetomidine group (any time initiation of dexmedetomidine from intubation).