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. 2022 Jan 18;53(2):363–371. doi: 10.1007/s11239-022-02631-7

Table 3.

Laboratory measurements

DM No DM (n = 73) p-value
Metformin (n = 34 No Metformin
(n = 41)
Metformin vs. no metformin Metformin vs. no DM No metformin vs. No DM
Creatinine (mg/dL) 1.1 ± 0.8 1.9 ± 3.6 1.1 ± 1.8 0.21 1.00 0.12
Glucose (mg/dL) 198 ± 82 190 ± 85 121 ± 62 0.68 < 0.0001  < 0.0001
Aspartate transaminase (u/L) 49 ± 31 64 ± 62 64 ± 88 0.20 0.34 1.00
Alanine transaminase (u/L) 49 ± 61 61 ± 68 55 ± 63 0.43 0.64 0.64
Alkaline phosphatase (u/L) 98 ± 88 93 ± 49 71 ± 26 0.76 0.02 0.002
Lactate dehydrogenase (U/L) 382 ± 108 439 ± 229 445 ± 357 0.19 0.32 0.92
Prothrombin time (secs) 14.6 ± 3.3 14.0 ± 3.1 14.9 ± 2.8 0.42 0.63 0.12
Total bilirubin (mg/dL) 0.56 ± 0.21 0.65 ± 0.64 0.61 ± 0.38 0.44 0.48 0.68
Albumin (g/dL) 3.7 ± 0.7 3.6 ± 0.7 3.9 ± 0.5 0.54 0.09 0.009
Platelet (× 1000/mm3) 262 ± 85 287 ± 154 257 ± 128 0.40 0.84 0.27
White blood cells (K/mm3) 8.6 ± 3.8 10.7 ± 3.8 8.4 ± 5.0 0.02 0.84 0.012
Haematocrit (%) 37 ± 6 37 ± 7 38 ± 6 1.00 0.42 0.42
Neutrophil/leukocyte ratio 9.3 ± 10.7 10.7 ± 9.2 8.3 ± 7.4 0.54 0.58 0.13
Hemoglobin (g/dL) 11.9 ± 2.1 11.7 ± 2.3 12.1 ± 2.3 0.70 0.67 0.37
HaemoglobinA1c 8.7 ± 2.3 8.5 ± 1.9 5.8 ± 0.8 0.68  < 0.001 < 0.001