Table 2.
Association between anthropometric measures and the risk of severe diabetic eye disease according to stages of diabetic nephropathy
| HR (95%CI) | z-value | P-value | |
|---|---|---|---|
| All individuals, n = 3468 | |||
| WHtR, per 0.1 increase | 1.28 (1.13-1.47) | 3.7337 | 0.0002 |
| WC, per 1-cm increase | 1.01 (1.00-1.02) | 3.0310 | 0.002 |
| BMI, per 1-kg/m2 increase | 1.03 (1.00-1.05) | 2.3267 | 0.020 |
| WHR, per 0.1 increase | 1.15 (1.02-1.29) | 2.2210 | 0.026 |
| Normo- and microalbuminuria, n = 3146 | |||
| WHtR, per 0.1 increase | 1.32 (1.15-1.52) | 3.8562 | 0.0001 |
| WC, per 1-cm increase | 1.01 (1.00-1.02) | 3.0360 | 0.002 |
| BMI, per 1-kg/m2 increase | 1.03 (1.01-1.06) | 2.7325 | 0.006 |
| WHR, per 0.1 increase | 1.13 (1.00-1.29) | 1.8892 | 0.059 |
Multivariable Cox regression model was adjusted for age at onset of diabetes, duration of diabetes, sex, glycated hemoglobin A1c, systolic blood pressure, triglycerides, smoking, lipid-lowering medication, any retinopathy except SDED, and estimated glomerular filtration rate. Diabetic nephropathy stage was also included as a covariate in the Cox regression model with all individuals.
Abbreviations: BMI, body mass index; WC, waist circumference; WHR, waist-hip ratio; WHtR, waist-height ratio.