Table 3.
Variables | Infusion | Group | Infusion | Interaction | |||
---|---|---|---|---|---|---|---|
Group | Younger | Middle-aged/older higher testosterone | Middle-aged/older lower testosterone | ||||
N | 20 | 20 | 18 | ||||
Baseline brachial artery diameter, mm | Saline | 4.1 ± 0.5 | 4.7 ± 0.6 | 5.0 ± 0.5 | <0.001 | 0.253 | 0.065 |
Vit C | 4.2 ± 0.5 | 4.7 ± 0.5 | 4.9 ± 0.6 | ||||
Brachial artery diameter change, mm | Saline | 0.32 ± 0.06 | 0.26 ± 0.10 | 0.19 ± 0.09 | <0.001 | 0.007 | 0.139 |
Vit C | 0.32 ± 0.07 | 0.31 ± 0.10 | 0.26 ± 0.07 | ||||
Allometrically scaled FMD, % | Saline | 6.8 ± 2.7 | 5.8 ± 1.8 | 4.1 ± 2.6 | 0.003 | 0.005 | 0.113 |
Vit C | 7.4 ± 2.2 | 7.0 ± 2.0 | 5.9 ± 2.1 | ||||
RHI | Saline | 1.76 ± 0.48 | 2.19 ± 0.57 | 2.14 ± 0.40 | 0.086 | 0.480 | 0.272 |
Vit C | 1.88 ± 0.51 | 2.07 ± 0.51 | 1.97 ± 0.45 | ||||
lnRHI | Saline | 0.53 ± 0.26 | 0.75 ± 0.25 | 0.74 ± 0.18 | 0.052 | 0.544 | 0.248 |
Vit C | 0.60 ± 0.26 | 0.69 ± 0.26 | 0.66 ± 0.19 |
Data examined using 2-way ANOVAs and displayed as mean ± SD.
Abbreviations: FMD, flow-mediated dilation; lnRHI, natural log–transformed reactive hyperemia index; RHI, reactive hyperemia index.