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. 2021 Oct 1;107(2):e500–e514. doi: 10.1210/clinem/dgab715

Table 3.

Vascular data

Variables Infusion Group Infusion Interaction
Group Younger Middle-aged/older higher testosterone Middle-aged/older lower testosterone
N 20 20 18
Baseline brachial artery diameter, mm Saline 4.1 ± 0.5 4.7 ± 0.6 5.0 ± 0.5 <0.001 0.253 0.065
Vit C 4.2 ± 0.5 4.7 ± 0.5 4.9 ± 0.6
Brachial artery diameter change, mm Saline 0.32 ± 0.06 0.26 ± 0.10 0.19 ± 0.09 <0.001 0.007 0.139
Vit C 0.32 ± 0.07 0.31 ± 0.10 0.26 ± 0.07
Allometrically scaled FMD, % Saline 6.8 ± 2.7 5.8 ± 1.8 4.1 ± 2.6 0.003 0.005 0.113
Vit C 7.4 ± 2.2 7.0 ± 2.0 5.9 ± 2.1
RHI Saline 1.76 ± 0.48 2.19 ± 0.57 2.14 ± 0.40 0.086 0.480 0.272
Vit C 1.88 ± 0.51 2.07 ± 0.51 1.97 ± 0.45
lnRHI Saline 0.53 ± 0.26 0.75 ± 0.25 0.74 ± 0.18 0.052 0.544 0.248
Vit C 0.60 ± 0.26 0.69 ± 0.26 0.66 ± 0.19

Data examined using 2-way ANOVAs and displayed as mean ± SD.

Abbreviations: FMD, flow-mediated dilation; lnRHI, natural log–transformed reactive hyperemia index; RHI, reactive hyperemia index.