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. 2022 Jan 4;12:792361. doi: 10.3389/fmicb.2021.792361

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Copyright © 2022 Yang, Wang, Cheng, Yang, Wu, Huang, Tian, Jia, Liu, Zhu, Chen, Zhao, Zhang, Ou, Mao, Gao, Sun, Yu and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DPV growth curve analysis of interfering UL11 in DEF cells. (A) In the transfection condition, DEF cells were transfected UL11 with shRNA37, shRNA126, shRNA218, and shRNAneo, respectively. After 24 h, cells were collected to do Western blot analysis. (B) Quantification of the UL11 downregulation ratio. **P < 0.01; ^nsP > 0.05. (C) The effect of the shRNAneo on the replication of DPV. ^nsP > 0.05. (D) Growth curve of the UL11 downregulated mutant. The DPV infection at 0.01 MOI. ****P < 0.0001.