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. 2022 Jan 4;12:792162. doi: 10.3389/fmicb.2021.792162

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Copyright © 2022 Muchaamba, Eshwar, Stevens, Stephan and Tasara.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Consequences of aa changing SNPs on 3D protein structure of Hpt (A–D) and PgdA (E–H). Black arrows highlight areas of most significant change. (D,H) 3D protein structure alignment. Key; for Hpt alignment (D) LI (green), LII (blue), and LIII (red). For PgdA alignment, (H) conserved chain regions are colored magenta, TM-score LI (0.9756), and LIII (0.9689) relative to LII.