Figure 3.
Adoptive transfer of NK+Mφs and NK-Mφs to estimate their function in vivo. NK+Mφs and NK-Mφs were adoptive transferred to naïve recipients. Mice receiving PBS only were used as control. After transfer, mice were challenged with 1×103 IFUs of C. muridarum. (A) The percentage of body weight changes in the three groups of mice. (B) The chlamydial loads in lung at day 7 post challenge infection. The mean of log10 transformed IFUs per lung is presented. (C) The pathology of lung tissue. The lung tissue sections were routinely stained with H&E and observed in ×200 and ×400 magnification under light microscopy. (D) The score of tissue inflammatory grades. One-way ANOVA was used to determine significant differences between different groups. (n=5) *P < 0.05, **P < 0.01, ***P < 0.001.